Silicon photonic microfluidic biosensor for monitoring renal dysfunction

Photonic nanostructure-based biosensors highly benefit label-free sensing technology. In this work, three different photonic sensing layers have been proposed for sensing the concentration of creatinine levels in the human body. Creatinine concentration level ranges from 80.9 μmol L−1 to 85.28 μmol L−1. In the structure 1 line defect, structure 2 is waveguide with a microcavity, and structure 3 is micropillar with increased radius. The proposed sensing system is operated between the wavelength range of 1323 nm to 1332 nm for structure 1, 1225 nm to 1234 nm for structure 2, and 1401 nm to 1404 nm. The simulation result showed maximum sensitivity for sensing structure 3 with increased micropillar radius. The maximum quality factor of 7025 is attained. Obtained result showed the feasibility of future fabrication in future. © 2023, The Author(s), under exclusive licence to The Optical Society of India.